Aciphex (rabeprazole sodium) is a proton pump inhibitor (PPI) to reduce stomach acid and is used for the treatment of gastroesophageal reflux disease (GERD), duodenal ulcers, and used in combination with antibiotics to treat Helicobacter pylori (H. Aciphex is available as generic termed rabeprazole sodium.
Rabeprazole, which has the highest pKa of all PPIs and is therefore least stable at neutral pH, is more rapidly converted to inhibit the proton pump as compared to omeprazole, lansoprazole or pantoprazole. In older parietal cells, rabeprazole can be as much as 10 times more potent that other proton pump inhibitors.
Furthermore, what is the brand name for rabeprazole? Pariet
is rabeprazole the same as esomeprazole?
Rabeprazole is a PPI that effectively provides symptom relief and healing, and prevents relapse, in patients with erosive GERD. Esomeprazole, the s-enantiomer of omeprazole, has demonstrated superior efficacy over omeprazole in healing and symptom resolution in patients with erosive and nonerosive reflux disease.
What over the counter drug is similar to Aciphex?
Prilosec is available over-the-counter (OTC) and as a generic. Side effects of Aciphex and Prilosec that are similar include diarrhea, gas, sore throat, and headache.
Is rabeprazole good for acid reflux?
Rabeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Rabeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).
Why is Razo 20 prescribed?
Why it’s used Rabeprazole is used to treat several gastrointestinal (GI) conditions. These include: heartburn and other symptoms related to gastroesophageal reflux disease (GERD). GERD occurs when acid in your stomach backs up into your esophagus (the tube that connects the mouth to the stomach).
Is rabeprazole more effective than pantoprazole?
CONCLUSIONS: In GERD patients with nocturnal heartburn, rabeprazole 20 mg was significantly more effective than pantoprazole 40 mg in percentage time with intragastric pH >4 during the nighttime, daytime, and 24-h periods.
Can you take rabeprazole and pantoprazole together?
Interactions between your drugs No interactions were found between pantoprazole and rabeprazole. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Which is better rabeprazole or omeprazole?
These data suggest that rabeprazole demonstrates a clinical advantage over omeprazole in symptomatic relief but no significant difference in endoscopic relief of erosive GERD for up to 8 weeks of treatment. Rabeprazole and omeprazole were both tolerated by GERD patients.
How long is it safe to take rabeprazole?
You should start to feel better within 2 to 3 days. But it may take up to 4 weeks for rabeprazole to work properly so you may still have some symptoms during this time. Is it safe to take rabeprazole for a long time? If you take rabeprazole for more than 3 months, the levels of magnesium in your blood may fall.
Which is better ranitidine and rabeprazole?
Rabeprazole was safe and well tolerated in this study. CONCLUSIONS: In patients with active duodenal ulcer disease, rabeprazole 20 mg q.a.m. is superior to ranitidine 150 mg b.i.d. in healing, resolving ulcer pain frequency, improving nighttime pain severity, and improving overall well-being.
Can I take 40mg of rabeprazole?
In patients with GERD and moderate to severe esophageal acid exposure, a dose of 20 mg and 40 mg per day of Rabeprazole Sodium Delayed-Release Tablets decreased 24-hour esophageal acid exposure.
Is esomeprazole better than other PPI?
The same studies demonstrated that esomeprazole 40 mg od is superior to all other PPIs at standard doses in terms of achieving higher 24-hour median intragastric pH and in terms of the number of patients achieving intragastric pH ≥4.0 for at least 12 hours per day.
What is the best PPI medication?
Pantoprazole is marketed as being cheaper, and may be better for patients paying for their own medications. Esomeprazole (Nexium), a new and very potent PPI, was approved by the U.S. Food and Drug Administration (FDA) in 2001. Zegerid is a combination of omeprazole and sodium bicarbonate.
What is rabeprazole sodium used for?
Aciphex (rabeprazole sodium) is a proton pump inhibitor (PPI) to reduce stomach acid and is used for the treatment of gastroesophageal reflux disease (GERD), duodenal ulcers, and used in combination with antibiotics to treat Helicobacter pylori (H. pylori) bacterial infections in the stomach.
Which is better esomeprazole or pantoprazole?
Esomeprazole 40 mg provided significantly greater healing than pantoprazole 40 mg after 4 weeks of treatment in patients with EE (56.36% vs. 49.09 %). Conclusion: Esomeprazole is more effective than pantoprazole for rapid relief of heartburn symptoms and acid reflux symptoms in patients with reflux esophagitis.
Is esomeprazole better than lansoprazole?
CONCLUSIONS: Esomeprazole (40 mg) is more effective than lansoprazole (30 mg) in healing erosive esophagitis and resolving heartburn. Healing rates are consistently high with esomeprazole, irrespective of baseline disease severity.
What can I take instead of Nexium?
If you have occasional heartburn and have not been diagnosed with GERD, your first and best bet is to try an inexpensive over-the-counter antacid like Maalox, Mylanta, Rolaids, Tums, or their generic equivalent or drugs like Pepcid AC or Zantac 150 or their generic equivalent (known as H2 blockers).